First Clone from Male Cells

Move over, Dolly. Researchers have broken another barrier in genetic research by successfully engineering the first clone using cells from a male mammal. Teruhiko Wakayama and Ryuzo Yanagimachi, who began cloning mice a year ago at the University of Hawaii at Manoa, used somatic (nonreproductive) cells from the tails of mice, showing that male as well as female clones could be produced from a variety of cells.

Researchers say the cloning could give hope to endangered species since fertility and sex are not factors. Previous cloning research has focused on cells related to female reproduction.

"Use of the tail cells indicates that it is possible to clone either sex, and probably from almost any kind of somatic cell, as long as one figures out a way to cause the cell to regress to a primitive state and capitulate gene effects," said Robert Foote, professor of animal physiology at Cornell University.